The Journal of Prolotherapy - For Doctors & Patients
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Article Abstract


 
The Ligament Injury Connection to Osteoarthritis
 



Osteoarthritis (OA) or degenerative joint disease (DJD) is more common than all the other types of arthritis combined. It is well-established that injury to a joint increases the chances that the joint will develop osteoarthritis over time. Precipitating causes include sudden impact or trauma, overuse or repetitive motion injuries, biomechanical abnormalities (congenital or acquired), ligamentous injury, joint hypermobility, obesity, intra-articular or systemic corticosteroids, avascular necrosis, and hereditary factors. Osteoarthritis, though the accepted term used to describe degenerative joint disease, is misleading because it primarily relates to cartilage, not bone, and involves degeneration, not inflammation. A lack of understanding about the development of osteoarthritis has resulted in a broad array of symptom-based treatment options such as rest, ice, heat, analgesics, anti-inflammatories, narcotics, braces and wraps, physical therapy and exercise, chiropractic, viscosupplementation, corticosteroid injections, and surgery. While advances have been made in joint replacement, cartilage repair, cartilage replacement, and spinal procedures, treatments to limit or even reverse articular cartilage breakdown have been lacking. Being that ligament injury, excess laxity, joint hypermobility, and clinical instability are known to be major causes of osteoarthritis, any treatment which can address restoration of ligament function would help reduce the incidence, pain, and dysfunction of osteoarthritis.



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