Prolotherapy for Lumbar Segmental Instability Associated with Degenerative Disc Disease

Posted on Posted in Degenerative Disc Disease, Volume 8 : 2016

Prolotherapy is an injection-based therapy that may be used in the management of chronic lower back pain. In principle, injection solutions are formulated to produce an inflammatory response, which in turn promotes ligamentous and tendonous regeneration. This case study series offers some ideas as to how Prolotherapy might be advantageous in the management of discogenic lower back pain through improving vertebral segmental stability. When the disc is of normal height, the ligaments that hold the spine together remain at normal length…

MRI Documented Improvement in Patient with Juvenile Osteochondritis Dissecans Treated with Platelet Rich Plasma

Posted on Posted in Budak Akman, MD, Volume 8 : 2016

Osteochondritis dissecans refers to the separation of osteochondral fragments from the bed of the joint surface. Definition of lesion goes by the existence of an open epiphyseal line in a juvenile form and the absence, representing an adult form. The treatment of osteochondritis dissecans depends on age, on the epiphyseal line, its length, location and stability of the lesion. A conservative treatment is preferred in juvenile cases; a surgical intervention may be necessary for unstable lesions and those not responding to conservative approaches…

Treatment of Trigeminal Neuralgia Utilizing Neural Prolotherapy: A Case Report

Posted on Posted in Volume 8 : 2016

Neural prolotherapy, as developed by Jon Lyftogt, has been found to be an effective treatment for neurogenic pain syndromes. We report a case of trigeminal neuralgia successfully treated with neural prolotherapy. The patient is a 70-year-old man with a 15-year history of trigeminal neuralgia refractory to pharmacologic treatment. After one treatment of neural prolotherapy the patient reported 5 months of complete resolution of his symptoms. A second treatment was performed affording him another 10 months of relief. Neural prolotherapy may have an important role in treating trigeminal neuralgia. It can be a safe and effective treatment for those experiencing side effects from medications, contraindications to surgery, or less than favorable improvement from traditional treatments.

Understanding Mechanical Emulsification (Nanofat) Versus Enzymatic Isolation of Tissue Stromal Vascular Fraction (tSVF) Cells from Adipose Tissue: Potential Uses in Biocellular Regenerative Medicine

Posted on Posted in Robert W. Alexander, MD, DMD, FICS, Volume 8 : 2016

With rapid growth of experiences and techniques in the field of Biocellular Regenerative Medicine, clinical scientists and biotechnical advancements constantly seek to understand and optimize uses of the multipotent heterogeneous cellular populations found in adipose tissue complex.

Clinical Outcome of Bone Marrow Concentrate in Knee Osteoarthritis

Posted on Posted in Chakrapani Pathikonda, David M. Crane, MD, Kristin S. Oliver, MD, Matt Bayes, MD, Volume 7 : 2015

Knee osteoarthritis is an increasing health concern in the adult population. Nonsurgical treatment options for pain reduction and function improvement are limited in number and provide only short-term relief. The potential of regenerative therapies to go beyond temporary symptom reduction and delay or negate the need for total knee joint arthroplasty is enticing to both patients and providers.

Upper Cervical Instability of Traumatic Origin Treated with Dextrose Prolotherapy: A Case Report

Posted on Posted in Volume 7 : 2015

Ross A. Hauser, MD1, Danielle R. Steilen, PA-C1 & Paul Fisher2 1Caring Medical Regenerative Medicine Clinics 2Gold Coast Chiropractic ABSTRACT Introduction: Ligamentous injury is widely viewed as a key to the pathophysiology of chronic neck pain. However, this hypothesis has little support with respect to data correlating patient status with either repair-promoting treatments or documentation more »

Direct Bone Marrow Injections for Avascular Necrosis of the Talus: A Case Report

Posted on Posted in Volume 4 : 2012

Avascular necrosis (AVN) of the talus is a debilitating condition, often leading to arthritis and arthrosis of the subtalar and ankle joints. There are three basic categories of cause for AVN. Approximately 10% of AVN of the talus is considered idiopathic: 15% is medication induced and 75% from trauma. The most feared complication of talar injuries is AVN.

Neural Prolotherapy for Neuralgia

Posted on Posted in Eileen Conaway, DO, Volume 6 : 2014

Mononeuralgia is pain along the distribution of a single peripheral nerve. Single nerve neuralgia is often caused by compression or other damage to the nerve, although in many cases a specific cause is not apparent. In instances where a structural cause is identified and corrected, patients may continue to experience pain in the affected nerve due to facilitation. This paper will discuss Neural Prolotherapy as a potential treatment for mononeuralgia by demonstrating cases of successful treatments for trigeminal neuralgia and meralgia paresthetica.

Efficacy of One Day Training in Low-Cost Manual Preparation of High Cellular Platelet Rich Plasma

Posted on Posted in K. Dean Reeves, MD, Volume 6 : 2014

Platelet rich plasma (PRP) is under investigation as a therapeutic injectate in a growing number of applications. Its production commonly involves proprietary materials and proprietary centrifuges. Manual PRP production has been described but training efficacy has not been demonstrated. A method to manually produce high quality PRP quickly, inexpensively and consistently, that is easily mastered, would afford the opportunity …

A Retrospective Study on Dextrose Prolotherapy for Unresolved Knee Pain at an Outpatient Charity Clinic in Rural Illinois

Posted on Posted in Volume 1 : Issue 1 : February 2009

By Ross A. Hauser, MD & Marion A. Hauser, MS, RD ABSTRACT The optimal long-term, symptomatic therapy for unresolved knee pain has not been established. Accordingly, we investigated the outcomes of patients undergoing Hackett-Hemwall dextrose Prolotherapy treatment for unresolved knee pain at a charity clinic in rural Illinois. We studied a sample of 80 patients, representing a total of 119 more »

Stabilization of Rheumatoid Thumb Interphalangeal Joint Boutonniere Deformity and Severe Subluxation with Splinting and Prolotherapy: A Case Report

Posted on Posted in Case Reports, Ross A. Hauser, MD, Shelby Ostergaard, Susan Santilli, OTR/L, CLT, Volume 4 : 2012

In this clinical case, a 57-year-old white female afflicted with rheumatoid arthritis received treatment for a 35-degree interphalangeal (IP) thumb joint deviation. The thumb deviation clinically described as a boutonniere (French for buttonhole) deformity was treated with a combination of Prolotherapy and splinting. She wore a custom three-point splint for six weeks and received three separate Prolotherapy treatments within that six-week period. After treatment, the deviation decreased from 35 degrees to 10 degrees, and her thumb pain decreased from 7 to 1 on a pain scale of 10 as the highest level.

A Case for Prolotherapy and Its Place in Veterinary Medicine

Posted on Posted in Babette Gladstein, VMD, Four-Legged Prolotherapy, Volume 4 : 2012

Pain management and the resolution of that pain has become the campaign of the current veterinary and pet owner communities. The fastest growing segment of our pet population is the aging dog and cat. Prolotherapy is one of the oldest, yet little known, modalities for resolution of pain and lameness. Prolotherapy is compared to its pharmacologic and surgical counterparts. This paper contrasts the current practices available for the resolution of common (ACL) knee injuries and (HD) hip dysplasia in the veterinary community. ACL injuries and HD are the two most prevalent and costly pathologies in modern veterinary practices across America. The science of Prolotherapy is brought into focus and compared with conventional solutions for soft tissue injuries and osteoarthritis. The objective of this paper is to make a case for Prolotherapy and emphasize its usage and application in veterinary medicine.

Understanding Adipose-derived Stromal Vascular Fraction (AD-SVF) Cell Biology and Use on the Basis of Cellular, Chemical, Structural and Paracrine Components: A Concise Review

Posted on Posted in Robert W. Alexander, MD, DMD, FICS, Volume 4 : 2012

In the past 10 years, biocellular regenerative medicine has recognized the potential value and availability of a heterogeneous, undifferentiated, nucleated cell population with the adipose tissue complex (ATC). With the recognition of higher mesenchymal stem cell concentrations, ease and safety of access, and the very heterogeneous undifferentiated cell populations in the native 3D adipose matrix, many researchers and clinicians are moving from bone marrow sources to the adipose complex.

Journal of Prolotherapy International Medical Editorial Board Consensus Statement on the Use of Prolotherapy for Musculoskeletal Pain

Posted on Posted in Babette Gladstein, VMD, Donna Alderman, DO, Garrett Swetlikoff, ND, Gary B. Clark, MD, MPA, George H. Kramer, MD, Gunter Baehnisch, MD, Joan Resk, DO, JD, John Neustadt, ND, Jörn Funck, MD, José Eleazar Calderón, MD, José Hector Salazar, MD, Mark Delaurentis, MD, Mark L. Johnson, MD, FACS, Mark T. Wheaton, MD, Peter J. Blakemore, DO, Robert Banner, MD, Rodney S. Van Pelt, MD, Ross A. Hauser, MD, Shaun Fauley, DVM, Volume 3 : Issue 4 : December 2011

By Ross A. Hauser, MD, Havil S. Maddela, BS, Donna Alderman, DO, Gunter Baehnisch, MD, Robert Banner, MD, Peter J. Blakemore, DO, José Eleazar Calderón, MD, Gary B. Clark, MD, Mark DeLaurentis, MD, Shaun Fauley, DVM, Jörn Funck, MD, Babette Gladstein, VMD,Mark L. Johnson, MD, FACS, George H. Kramer, MD, John Neustadt, ND, Joan Resk, DO, JD, José Hector Salazar, MD, Garret Swetlikoff, ND, Rodney S. Van Pelt, MD, & Mark T. Wheaton, MD more »

Comprehensive Scientific Overview on the Use of Platelet Rich Plasma Prolotherapy (PRPP)

Posted on Posted in Karina Gordin, BA, MS, Volume 3 : Issue 4 : December 2011

By Karina Gordin, BA, MS ABSTRACT As noted in this review, over the past decade substantial advancements have been made in optimizing musculoskeletal diagnoses and repair. As a result, the research trend has evolved to recognize preventative measures and innovative treatments, which ultimately aim to improve patient quality of life and reduce the costly social impact more »

The Ligament Injury-Osteoarthritis Connection: The Role of Prolotherapy in Ligament Repair and the Prevention of Osteoarthritis

Posted on Posted in Mark T. Wheaton, MD, Nichole Jensen, BS, Volume 3 : Issue 4 : December 2011

By Mark T. Wheaton, MD & Nicole Jensen, BS ABSTRACT Ligaments are specialized bands of fibrous connective tissue which hold bones in approximation, providing mechanical support and stability across a joint to allow for fluid joint motion and prevent excessive joint displacement. When ligaments are injured, structural, mechanical and physiologic changes occur and joint stability is compromised. A more »

The Case for Prolotherapy – The Closing Argument

Posted on Posted in Volume 3 : Issue 4 : December 2011

By Julie R. Gunnigle, JD Chronic pain can dominate a patient’s life. From the physiological disability of being unable to perform daily activities, to the financial cost of missed work and expensive procedures, the pain can quickly spread from the body to the pocketbook. Left unresolved, pain can dominate every aspect of life, robbing patients of more »