Knee osteoarthritis is an increasing health concern in the adult population. Nonsurgical treatment options for pain reduction and function improvement are limited in number and provide only short-term relief. The potential of regenerative therapies to go beyond temporary symptom reduction and delay or negate the need for total knee joint arthroplasty is enticing to both patients and providers.
Platelet rich plasma (PRP) is under investigation as a therapeutic injectate in a growing number of applications. Its production commonly involves proprietary materials and proprietary centrifuges. Manual PRP production has been described but training efficacy has not been demonstrated. A method to manually produce high quality PRP quickly, inexpensively and consistently, that is easily mastered, would afford the opportunity …
The Achilles tendon is the largest and strongest tendon in the human body, and a common site for injury and disease.
By Donna D. Alderman, DO, Robert W. Alexander, MD, DMD, FICS, Gerald R. Harris, DO, & Patrick C. Astourian, MS, PA-C ABSTRACT Prolotherapy is a proven technique for resolving musculoskeletal pain, but can have limitations if tissue damage is too severe. Platelet Rich Plasma (PRP) Prolotherapy offers a physiologic tool in some of those cases, but this too may more »
By Kristin S. Oliver, MD, MPH & David M. Crane, MD ABSTRACT Platelet Rich Plasma (PRP) grafts are growing in popularity in the musculoskeletal arena. This article explains the risks and considerations for using PRP in the clinical setting, in addition to the authors’ method of preparing a PRP graft. This article reviews the basic biology of platelets and more »
By Gary B. Clark, MD, MPA Visions of Regenerations to Come “Sometime between the years 1934 and 1936, a random patient with a random disease visited a random doctor and for the first time in recorded human history had a better than 50:50 chance of benefiting from the encounter.” –Anonymous The above-cited quotation still lies sequestered more »
By Ross A. Hauser, MD & Marion A. Hauser, MS, RD ABSTRACT This article provides the JOP reader with some basic information about Platelet Rich Plasma, also known as PRP. PRP as a Prolotherapy proliferant has become increasingly popular in the pain management field. The basic tenants of PRP preparation and use in the Prolotherapy field are discussed. more »