Chondromalacia patella is a musculoskeletal pain disorder in which degeneration of cartilage underneath the patella can induce symptoms of pain, stiffness, and crepitus. If left untreated, it can often lead to knee osteoarthritis. Current treatments for chondromalacia patella (physical therapy, NSAIDs, etc.) are often ineffective and sometimes detrimental to the health of the knee. A proposed, alternative treatment currently provided to some patients is Prolotherapy, an injection technique used to stimulate the growth of new cells, including connective tissue.
The sacroiliac joint (SIJ) can become dysfunctional through trauma and/ or pregnancy. The mechanism involves direct or repetitive microtrauma to the buttocks/ lower back. Treatment with specialised physiotherapy alleviates the problems in ~ 80% of cases. The remainder may respond to prolotherapy (hypertonic glucose injections into the dorsal intra-osseous ligament (DIOL) after multiple injections.
Impingement of the medial branch of the superior cluneal (MBSC) nerves are thought to be an overlooked cause of low back pain, with this impingement occurring where the branches of these nerves pass over the superior rim of the iliac crest in osseofibrous tunnels formed by the thoracolumbar fascia.