Comprehensive Scientific Overview on the Use of Platelet Rich Plasma Prolotherapy (PRPP)

Posted on Posted in Karina Gordin, BA, MS, Volume 3 : Issue 4 : December 2011

By Karina Gordin, BA, MS ABSTRACT As noted in this review, over the past decade substantial advancements have been made in optimizing musculoskeletal diagnoses and repair. As a result, the research trend has evolved to recognize preventative measures and innovative treatments, which ultimately aim to improve patient quality of life and reduce the costly social impact more »

The Ligament Injury-Osteoarthritis Connection: The Role of Prolotherapy in Ligament Repair and the Prevention of Osteoarthritis

Posted on Posted in Mark T. Wheaton, MD, Nichole Jensen, BS, Volume 3 : Issue 4 : December 2011

By Mark T. Wheaton, MD & Nicole Jensen, BS ABSTRACT Ligaments are specialized bands of fibrous connective tissue which hold bones in approximation, providing mechanical support and stability across a joint to allow for fluid joint motion and prevent excessive joint displacement. When ligaments are injured, structural, mechanical and physiologic changes occur and joint stability is compromised. A more »

Tensegrity to Tendinosis

Posted on Posted in Thomas Ravin, MD, Volume 3 : Issue 4 : December 2011

By Thomas Ravin, MD ABSTRACT Biotensegrity or hierarchical tensegrity can explain how prestressed structures function in animals to transfer the stresses created by gravity, movement, digestion and emotional factors to the extracellular matrix (ECM). Tensegrity’s connection to the ECM is explored, and the mechanotransduction of signals that prompt cellular changes in entheses, ligaments and tendons is more »