Chondromalacia patella is a musculoskeletal pain disorder in which degeneration of cartilage underneath the patella can induce symptoms of pain, stiffness, and crepitus. If left untreated, it can often lead to knee osteoarthritis. Current treatments for chondromalacia patella (physical therapy, NSAIDs, etc.) are often ineffective and sometimes detrimental to the health of the knee. A proposed, alternative treatment currently provided to some patients is Prolotherapy, an injection technique used to stimulate the growth of new cells, including connective tissue.