Understanding Adipose-derived Stromal Vascular Fraction (AD-SVF) Cell Biology and Use on the Basis of Cellular, Chemical, Structural and Paracrine Components: A Concise Review

Posted on Posted in Robert W. Alexander, MD, DMD, FICS, Volume 4 : 2012

In the past 10 years, biocellular regenerative medicine has recognized the potential value and availability of a heterogeneous, undifferentiated, nucleated cell population with the adipose tissue complex (ATC). With the recognition of higher mesenchymal stem cell concentrations, ease and safety of access, and the very heterogeneous undifferentiated cell populations in the native 3D adipose matrix, many researchers and clinicians are moving from bone marrow sources to the adipose complex.

Stem Cell Prolotherapy in Regenerative Medicine: Background, Theory and Protocols

Posted on Posted in Donna Alderman, DO, Gerald R. Harris, DO, Patrick C. Astourian, MS, PA-C, Robert W. Alexander, MD, DMD, FICS, Volume 3 : Issue 3 : August 2011, Wonder Why?

By Donna D. Alderman, DO, Robert W. Alexander, MD, DMD, FICS, Gerald R. Harris, DO, & Patrick C. Astourian, MS, PA-C ABSTRACT Prolotherapy is a proven technique for resolving musculoskeletal pain, but can have limitations if tissue damage is too severe. Platelet Rich Plasma (PRP) Prolotherapy offers a physiologic tool in some of those cases, but this too may more »